Simulations of pharmacological actions in the basal ganglia circuit
نویسندگان
چکیده
We have carried out computational simulations to investigate pharmacological effects in the basal ganglia (BG). Results of our simulations showed that dopamine depletion induces a time delay of the saccade eye movements and an oscillatory behavior of the neuronal activity in the BG. We also suggest that the oscillatory behavior is originated from formation of closed loop circuits in the BG.
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